The Buffalo Bills will play their first game at Highmark Stadium under the lights of prime time.
They’ll host the Detroit Lions on Thursday Night Football in Week 2 for their home opener.
The matchup will mark the first meeting between the two teams since they combined for 90 points in a 48-42 victory for Buffalo in Week 15 of the 2024 season.
The Bills have won their last four home openers. They also played a prime-time game for their home opener last year, beating the Baltimore Ravens 41-40 on Sunday Night Football in Week 1.
The NFL will reveal the full 2026 schedule on Thursday at 8 p.m. ET.