The Tampa Bay Buccaneers might have parted ways with former No. 1 overall draft pick Jameis Winston after five seasons because of turnovers. Yet with Winston now in a Saints uniform, it was new quarterback Tom Brady who struggled and turned over the ball in his Buccaneers debut Sunday.

The six-time Super Bowl winner threw two interceptions, including a pick-six, in a 34-23 loss to the host New Orleans Saints. It was just his fourth loss in a season opener. And it was the third consecutive game in which he threw a pick-six (last season’s AFC wild-card game vs. the Tennessee Titans and a Week 17 loss to the Miami Dolphins, both while with the Patriots).

It marked Brady’s first multi-interception game in an opener since 2003 (he threw four interceptions against the Bills in Week 1) and his first pick-six in an opener since 2009.

“It’s a game of execution. Obviously they made more plays than we did, and I made just some bad, terrible turnovers,” said Brady, who, at age 43, made his 325th career start, the most regular-season and postseason combined starts in NFL history. “It’s hard to win, turning the ball over like that. So I’ve obviously gotta do a lot better job.”

Brady completed 23 of 36 passes for 239 yards and two touchdowns, while scoring a third on the ground. The rush — a 2-yard QB keeper up the middle — was set up by a play-action, 29-yard pass to Chris Godwin to make it 7-0.

“He came out, lighting it up, went down the field and scored a touchdown, so I wouldn’t say he was out of sync at all ’til we started screwing it up,” coach Bruce Arians said.

But his two picks were costly.

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